Ledong Wan Research Lab

Ledong Wan, PhD

• Assistant Professor, Department of Pharmacological Sciences, Renaissance School of Medicine

My Lab

Office: (631) 722-2623

Email: ledong.wan@stonybrookmedicine.edu

Stony Brook University
Department of Biomedical Informatics
100 Nicolls Road
Stony Brook, NY 11794

Research Program

• Oncogenic Drivers and Mechanisms of Carcinogenesis

Department

• Department of Pharmacological Sciences

Research Interest

• RNA Metabolism, Pancreatic Cancer, Inflammation

Our laboratory seeks to understand the mechanisms by which RNA splicing is dysregulated to promote tumorigenesis and progression. We utilize transgenic mouse models and organoid culture to investigate the regulation of RNA splicing in physiological conditions and its dysregulation in inflammation and pancreatic cancer. Our expertise in small molecules and antisense technology enables us to modulate aberrant splicing for potential cancer therapy.

Education

• BS, Pharmacology, China Pharmaceutical University, Nanjing, 2011
• MS, Medicinal Chemistry, China Pharmaceutical University, 2014
• PhD, Pathology and Pathophysiology, Zhejiang University, 2018
• Postdoctoral training, Cold Spring Harbor Laboratory, New York, 2018 - 2023 

Publications

• View a complete list of publications.