Peng Mao Research Lab

Peng Mao, PhD

Peng Mao, PhD

  • Associate Professor, Department of Pathology, Renaissance School of Medicine

My Lab

Email: peng.mao@stonybrookmedicine.edu

Stony Brook Medicine
Department of Pathology
Basic Science Tower, Level 9, Room 9-150
Stony Brook, NY 11794

Research Program

Department

Research Interest

The Mao lab uses next-generation sequencing (NGS) and bioinformatics methods to study where DNA damage is formed in the genome and how it is repaired. Current research interests include: 

  • How do DNA repair proteins function in chromatin to remove DNA damage? 
     
  • How does the transcription machinery, including transcription factors, elongating RNA polymerase, and histone modification enzymes, impact different DNA repair pathways? 
     
  • How do cancer cells selectively modulate DNA repair pathways to tolerate chemotherapeutic agents?

Addressing these questions will not only provide new insights into the fundamental mechanism of DNA repair system, but shed light on new strategies to sensitize drug-resistant tumors by inhibiting specific DNA repair pathways.

Education

  • BS, Huazhong University of Science and Technology, China
  • PhD, Peking University, China
  • Postdoc, Washington State University, Pullman, Washington

Publications

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