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Oligodendroglioma

Oligodendroglioma is a rare brain tumor that begins in glial cells called oligodendrocytes. These tumors are usually slow-growing but can spread into nearby brain tissue, which can make complete removal difficult. They rarely spread outside the brain or spinal cord. 

Types & Stages 

Oligodendrogliomas are grouped by grade:

  • Grade II (low-grade): Slow-growing and often present for years before causing symptoms. They usually respond well to treatment.
     
  • Grade III (anaplastic/high-grade): Faster-growing, more aggressive malignant tumors that are harder to treat.
     

Signs & Symptoms

Common symptoms may include: 

  • Seizures
  • Balance problems
  • Memory problems
  • Changes in behavior
  • Trouble speaking
  • Difficulty thinking clearly
  • Numbness on one side of the body

Diagnosis  

Diagnosis may involve:

  • Neurological exam
  • MRI or other imaging tests
  • Biopsy to confirm the tumor type

Treatment

Treatment options may include:

  • Surgery to remove as much of the tumor as possible
  • Radiation therapy
  • Chemotherapy

Risk Factors

Possible risk factors include:

  • Age (most common in adults in their 40s and 50s)
  • Prior radiation exposure to the head or neck
  • Race (most common in white people who do not have Hispanic ancestry)

Screening

There is no routine screening for oligodendroglioma. Diagnosis depends on symptoms and medical evaluation.


Visit the Neurologic Oncology team page
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