Office
(631) 632-1903
Email
ed.luk@stonybrook.edu
Stony Brook University
Department of Biochemistry and Cell Biology
410 Life Sciences Building
100 Nicolls Road
Stony Brook, NY 11794-5215
Ed Luk, PhD
Associate Professor, Department of Biochemistry and Cell Biology,
Stony Brook University
Research Program
Oncogenic Drivers and Mechanisms of CarcinogenesisDepartment
Department of Biochemistry and Cell BiologyResearch Interest
Histone proteins are major constituents of the chromosome. DNA wraps around histones to form repeating structural units called nucleosomes. Nucleosomes can then stack onto each other to fold the genomic DNA into a compact, organized structure within the nucleus. For the transcription machinery to ‘read’ the underlying genetic information, the histones must be reorganized and removed at some points. We study the molecular events that mobilize histones to allow the transcription machinery to engage the DNA and turn a gene on or off.
Education
BS: University of MichiganPhD: Johns Hopkins University