Office
Email
peng.mao@stonybrookmedicine.edu
Stony Brook Medicine
Department of Pathology
Basic Science Tower, Level 9, Room 9-150
Stony Brook, NY 11794
Peng Mao, PhD
Associate Professor, Department of Pathology
Renaissance School of Medicine at Stony Brook University
Research Program
Oncogenic Drivers and Mechanisms of CarcinogenesisDepartment
Department of PathologyResearch Interest
The Mao lab uses next-generation sequencing (NGS) and bioinformatics methods to study where DNA damage is formed in the genome and how it is repaired. Current research interests include: (1) How do DNA repair proteins function in chromatin to remove DNA damage? (2) How does the transcription machinery, including transcription factors, elongating RNA polymerase, and histone modification enzymes, impact different DNA repair pathways? (3) How do cancer cells selectively modulate DNA repair pathways to tolerate chemotherapeutic agents? Addressing these questions will not only provide new insights into the fundamental mechanism of DNA repair system, but shed light on new strategies to sensitize drug-resistant tumors by inhibiting specific DNA repair pathways.
Education
BS: Huazhong University of Science and Technology, China
PhD: Peking University, China
Postdoc: Washington State University, Pullman, WA