Janet Allopenna

imageSr. Research Support Specialist / Lab Manager

Education:  
BS – Biology: S.U.N.Y. @ Binghamton, N.Y. (1984)
MA – Biology: Hunter College, New York, N.Y. (1993)

Contact Info:
Janet Allopenna
The Lipid Cancer Lab
Department of Medicine
MART Bldg., Floor-9S
Stony Brook University Medical Center
Stony Brook, NY 11794-7294
(631) 216-2912
Janet.Allopenna@stonybrookmedicine.edu

   
Publications:

  • Sakamoto W, Canals D, Salamone S, Allopenna J, Clarke CJ, Snider J, Obeid LM, Hannun YA.  (2019)  Probing compartment-specific sphingolipids with targeted bacterial sphingomyelinases and ceramidases. J. Lipid Research 60(11):1841-1850.

  • Senkal, Can E., Salama, Mohamed F., Snider, Ashley J., Allopenna, Janet J., Rana, Nadia A., Koller, Antonius, Hannun, Yusuf A., Obeid, Lina M.  (2017)  Ceramide Is Metabolized to Acylceramide and Stored in Lipid Droplets. Cell Metabolism 25:686-697.

  • Catherine Salussolia, Quan Gan, Rashek Kazi, Puja Singh, Janet Allopenna, Hiro Furukawa, and Lonnie Wollmuth.  (2013)  A Eukaryotic Specific Transmembrane Segment is Required for Tetramerization in AMPA Receptors.  J. Neurosci. 33(23):9840-9845.

  • Dallman, J.E., Allopenna, J., Bassett, A., Travers, A., Mandel, G.  (2004)  A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation.  J. Neurosci. 24(32):7186-7193.
  • Kitareewan, S., Spinella, M.,  Allopenna, J.,  Reczek, P., Dmitrovsky, E.  (1999)  4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RAR gamma independent pathway.  Oncogene 18:5747-5755.
  • Nason-Burchenal, K.,  Allopenna. J.,  Begue, A.,  Stehelin, D.,  Dmitrovsky, E.,  Martin, P.  (1998)  Targeting Of PML/RAR alpha is lethal to retinoic acid resistant promyelocytic leukemia cells.  Oncogene 17(14):1759-68.
  • Nason-Burchenal, K.,  Tackle, G.,  Pace, U.,  Flynn, S.,  Allopenna, J.,  Martin, P., George, S.T., Goldberg, A.R., Dmitrovsky, E.  (1998) Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells.  Oncogene 92(5):1758-67.
  • Nason-Burchenal, K.,  Maerz, W.,  Albanell, J.,  Allopenna, J.,  Martin, P.,  Moore, M.A.S.,  Dmitrovsky, E.  (1997)   Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.  Differentiation 61(5):321-331.
  • Nason-Burchenal, K.,  Gandini, D.,  Botto, M.,  Allopenna, J.,  Seale, J.R.C.,  Cross, N.C.P.,  Goldman, J.M.,  Dmitrovsky, E.,  Pandolfi, P.P.  (1996)   Interferon augments PML and PML/RAR alpha expression on normal myeloid and acute promyelocytic cells and cooperates with all-trans-retinoic acid to induce maturation of a retinoid resistant promyelocytic cell line.  Blood 88(10):3926-3936.
  • Kurie, J.M.,  Allopenna, J.,  Dmitrovsky, E.  (1994)   Retinoic acid stimulates protein kinase A-associated G proteins during human teratocarcinoma differentiation.  Biochemica et Biophysica Acta 1222(1):88-94.
  • Levine, S.,  Xian, C.Y.,  Agocha, B.,  Allopenna, J.,  Welte, K.,  Armstrong, D.,  Yang, S.Y.,  Evans, R.L.  (1991)   Differential modulation of the CD-2 and CD-3 T-cell activation pathways by a monoclonal antibody to Leu 13.  Cell. Immunol. 132(2):366-376.
  • Kato, K.,  Trapani, J.A.,   Allopenna, J.,  Dupont, B.,  Yang, S.Y.  (1989)   Molecular analysis of the serologically defined HLA-Aw19 antigens.  A genetically distinct family of HLA-A antigens comprising A29, A31, A32 and Aw33, but probably not A30.  J. Immunol.  143(10):3371-3378.
  • Fukinaga, Y.,  Evans, S.S.,  Yamomoto, M.,  Ueda, Y.,  Tamura, K.,  Takajuwa, T.,  Gebhard, D.,  Allopenna, J.,  Demaria, S.,  Clarkson, B.,  Thompson, L.F.,  Safai, B., Evans, R.L.  (1989)   Increased density of ecto 5' nucleotidase antigen on leukemic T-cells from patients with cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma.   Blood 74(7):2486-2492.

Acknowledgements:

  • Talukder, I., Kazi, R., Wollmuth, L.P. (2011). GluN1-specific redox effects on the kinetic mechanism of NMDA receptor activation. Biophysical J. 101: 2389-2398.
  • Salussolia, C.L., Corrales, A., Talukder, I., Kazai, R., Akgul, G., Bowen, B., Wollmuth, L.P. (2011) Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid (AMPA) receptors. J. of Biological Chem. 286(46): 40205- 40218.
  • Salussolia, C.L., Prodromou, M.L., Borker, P., Wollmuth, L.P. (2011). Arrangement of subunits in functional NMDA receptors. J. Neuroscience. 31(31): 11295-11304.
  • Talukder, I., Wollmuth, L.P. (2011). Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening. J. Gen. Physiol. 138(2): 179-194.
  • Akgul, G., and Wollmuth, L.P. (2010). Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex. J. of Comparative Neuroscience: 4842-4854.
  • Prieto, M.L., Wollmuth, L.P. (2010). Gating Modes in AMPA Receptors. J. Neuroscience. 30(12): 4449-4459.
  • Gleason, M.R., Armisen, R., Verdecia, M.A., Sirotkin, H., Brehm, P., Mandel, G. (2004). A mutation in serca underlies motility dysfunction in accordian zebrafish. Developmental Biology. 276: 441-451. 

  • Grimes JA., Nielsen SJ., Battaglioli E., Miska EA., Speh JC., Berry DL., Atouf F., Holdner BC., Mandel G., Kouzarides T.  (2000). The co-repressor mSin3A is a functional component of the REST-CoREST repressor complex. J Biol Chem. 275(13):9461-7.

  • E Early, M A Moore, A Kakizuka, K Nason-Burchenal, P Martin, R M Evans, and E Dmitrovsky. (1996). Transgenic expression of PML/RARalpha impairs myelopoiesis.  PNAS. 93 (15) 7900-7904.