PhD Candidate
Molecular and Cellular Biology
Education:
BA: Biochemistry, 2008. Macaulay Honors College of City University of New York
MA: Biochemistry, 2011. Hunter College, City University of New York
Project Description or Research Interest:
I am studying the downstream effects of Neutral Sphingomyelinase 2. It is an enzyme involved in hydrolysis of sphingomyelins to generate ceramides. Recent work in our lab has shown that this enzyme is upregulated by Doxorubicin in a p53 dependent manner and results in cell growth arrest. The focus of my research is to understand the downstream signaling pathway by which ceramide generated by nSMase2 affects the cellular response to DNA damage and how this pathway may be involved in cancer cells evading apoptosis.