Office
631-444-9364
Email
Ryan.Williams@stonybrookmedicine.edu
Stony Brook University
Health Sciences Center 15-103
Stony Brook, NY 11794-XXXX
Ryan Williams, PhD
SUNY Empire Innovation Associate Professor
Associate Director of Translation and Commercialization
Department of Medicine, Division of Nephrology & Hypertension
Renaissance School of Medicine at Stony Brook University
Research Program
Oncogenic Drivers and Mechanisms of Carcinogenesis
Department
Department of Medicine, Division of Nephrology & Hypertension
Research Interest
Our laboratory is focused on the design and translation of diagnostic and therapeutic nanomedicines. We primarily work on applications in cancer and kidney diseases, many of which are side effects of cancer treatments. Specifically, we have designed fluorescent nanosensors which can quantify concentrations of breast cancer biomarkers, inflammatory cytokines, or anti-tumor chemotherapeutics in live rodent models of disease. We anticipate translating these tools to the clinic as personalized implantable or bedside-use diagnostics or as research tools to improve disease biology and drug pharmacology. In addition, we have designed polymeric mesoscale nanoparticles which selectively target the kidneys. We are using these as delivery tools to treat chemotherapy- and surgery-induced kidney injury, chronic inflammatory kidney diseases, genetic kidney diseases, and kidney cancer.
Education
BA, Biology, University of Virginia, Charlottesville, Virginia
PhD, Pharmaceutical and Pharmacological Sciences, West Virginia University, Morgantown, West Virginia
Postdoctoral Fellowship, Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York
Publications
A complete list of publications can be found here.