Instrumentation

Protein and peptide analysis

  • Thermo Q-Exactive HF (Q-Orbitrap); Thermo 1200 nano easyLC 
  • Sciex 5600Plus – quadrupole time-of-flight (QqTOF); with nanoHPLC
  • Thermo LTQ linear ion trap; with HPLC
  • Bruker rapiFLEX for protein analysis

Lipid analysis

  • Thermo TSQ Quantiva - triple quadrupole with uHPLC (Vanquish)
  • Thermo TSQ Quantum Ultra – triple quadrupole with HPLC [2]
  • Bruker TimsTOF and rapiFLEX for lipid tissue scanning

PK and metabolite analysis

  • Bruker TimsTOF and rapiFLEX for drug and metabolite tissue scanning
  • Sciex 5600+ with uHPLC
  • Thermo TSQ Quantum Access MAX – triple quadrupole with HPLC
  • Agilent triple quadrupole with HPLC
  • Agilent GC-MS

Bioinformatics: Dell workstations, ProteinPilot, MaxQuant, GPM, Proteome Discoverer