Mechanism of Carcinogenesis and Molecular Medicine
April 16, 2024
8 am - 4:45 pm
The Waterview, Port Jefferson
Significant strides have been made in understanding the mechanisms, diagnosis, and treatment of cancers. Despite these advancements in cancer research and clinical practices, cancer remains the second leading cause of death in the US, following heart disease. Cancer, characterized by the uncontrolled growth and division of cells, has traditionally been attributed to accumulated genetic mutations in stem or somatic cells, deemed largely unpreventable. However, emerging evidence suggests that non-genetic factors, such as epigenetic changes, play a pivotal role in initiating carcinogenesis, particularly in response to non-mutagenic environmental factors. This revelation implies that many types of cancer are, indeed, preventable. The rapid progress in omics technologies and the integration of big data analytics in preclinical, translational, and clinical studies have unveiled previously unseen aspects of tumor landscapes, offering new avenues in molecular medicine for combating human cancers. Moreover, the convergence of single-cell methodologies, advanced computational techniques, and cutting-edge preclinical and translational endeavors has been instrumental in unraveling the complex interplay among genetics, epigenetics, cancer cells, stromal elements, the immune system, and external influencers such as diet and environmental conditions. At this year’s Gloria and Mark Snyder Symposium on Mechanisms of Carcinogenesis and Molecular Medicine, keynote speakers and other participants will present a comprehensive overview of how various factors shape the broader tumor ecosystem in space and time during malignant progression and therapeutic responses. This holistic understanding is crucial for the development of innovative diagnostic methods and therapeutic interventions, ranging from targeted therapies to immunotherapies.
Registration for the 2024 Research Symposium is now Closed. Any questions regarding cancelation please contact Lauren Cutaia 631-444-8067 or email lauren.cutaia@stonybrookmedciine.edu.